On top of timing, and different use of esoteric m68k'isms between the two:
Targets: There are very few actually different Amiga hardware models (even the 500 and the 2000 are almost identical, even if looking radically different), similarly fewer (and very clear) rom versions. Whereas even Macs that look similar have radically different hardware, and, for a while, every model had their own rom.
Connector: On the 500/2000 it physically replaces the 8 mhz 68000 chip, on the 1200 it uses the equivalent of a PDS slot. There has been some "success" getting a pistorm to work on 68000 based macs like SE's, but for all others you'll want to use a PDS (which, again, is radically different on different models) or something like a bus mastering nubus card. Not a lot of knowledge/people making Mac cards these days. Or, if you wanted to sit in the 030 or 040 socket (for macs WITH sockets), you'd need a completely new design...it wouldn't physically fit in the case, etc etc.
Apathy: Apple users got PowerMacs which, out of the box pretty much "are Macs" with a better CPU, but with seamless compatibility and excellent emulation. An m68k Mac with a PiStorm wouldn't be much different than that, if you think about it. Whereas PowerPC came to Amiga only in...very strange ways...in no way seamless, I'm simplifying, but there never was a "PowerAmiga", instead basically powerpc coprocessors on a card, or powerpc machines with no legacy amiga hardware at all. There were vast numbers of 500's and 2000's out there, using slow 8mhz 68000's, so a huge market. Most m68k mac users had far faster 030's, or just got powermacs and were satisfied.