Talk to Uniserver, he has brought boards back from the dead that you wouldn't think possible.
Also, I'd say, at a minimum, your R48 & R45 are blown to smithereens. Those two look like they took out R44, R47, & R49 in the process. Anything before R45 is probably gone, and anything in between R45 & R48 is probably also gone. Its hard to say how far beyond R48 the damage goes.