I installed on a IIcx, disabled macgetty, added the System Enabler 001 to both the boot drive and the AUX drive, then put the drive into my IIvx.
You can't use the Mac environment, perhaps if you added a Toby card you could.
It did work but the OS had a problem with the internal video of the IIvx, so hence why the installer itself didn't work, and macgetty locked up. If you telneted in a gave macgetty a polite signal it would wake up and continue.
It did work happily with an Asante NuBus ethernet, and the screen in the old terminal mode. I was able to telnet and ftp happily to the box and do compilations etc. I eventually removed the keyboard and mouse and just had it booting headless.