Most of these only really have drivers and integration for DOS+Windows 3 and Windows 95. Some of the later Orange Micro ones were made a little more generic, but as far as I know, that probably only officially extends to Windows NT. If it works at all, few people run Linux on these things because from a practical perspective, you wouldn't get much out of it relative to linux in Virtual PC on a faster Mac or using macssh or a telnet program to connect to a box on your network.
I'm sure you
could play some DOS/Windows games on them, but largely because they needed to be even a little bit affordable and because you are putting most of an entire physical computer inside another one, they aren't particularly high performance. Even without being very high performance, in some systems (the 6100 in particular, I don't know how the 630/610 are for this) these cards introduce a lot of heat.
The intent when they were new was absolutely to make midrange Macs being used in business and high end home office scenarios compatible with business and office applications - basically, the same use cases as VMware when the Intel Macs first launched, and Virtual PC, once Macs were fast (and stable) enough that you could just leave an entire Windows system running in the background.
Be aware that many of Apple's own DOS compatibility cards are specific to certain machines. For example, there's the one for the 630, and there's the one for the 610, and there's the one for the 6100, and after that they get
a little bit more generic, but not a lot. (In particular, I believe Apple's PCI compatibility cards require a port that is present on the 4400, 5400, 6400, 5500, 6500, 7200, 8500, 7500, and maybe the 7600 and 7300, but not the 9500 and 9600, and I forget if the 8600 has it.
I have a 6100/DOS and I'm interested in getting my card up and running, I believe
@LaPorta put the files up on VTools, so my only excuse is really that I haven't had the time or energy to pull the 6100 back out, put it up somewhere, network it to vtools and configure the stuff. I should see if I can do that soon, because I like that system and I have wanted to play Windows 3.
One of the PCI DOS cards in a machine like a 6400 or 7200 might be a better compromise if you wanted to build a "fast" Windows 3 or 95 configuration, because those have newer and faster CPUs and better hard disks and i/o in general than 68k and first-gen PPC Macs. You could do, say, a 7200 build with a PC card and a SCSI/IDE/SATA card and the attendant hard disk, (you could even do two disks - one for Mac data and a separate one for PC card data), and some other nicety such as a USB card.
For example:
https://modelrail.otenko.com/apple/power-mac-7200-pc-compatibility