You didn't mention the Macs to which the external drive may be attached. This can be significant, depending as the Mac(s) have a single internal/external bus or both internal and external buses. If there is only one bus, the external drive must have a different SCSI ID from that of any other drive in your system. Given that the purposes of external drives are often for backup or troubleshooting, SCSI ID=6 is often useful—because the system polls downward from ID=7 (the host, or the Mac itself) to ID=0, the default for a single internal HDD—to ensure that the system boots from the external drive when you select it with the four-fingered salute (control-option-shift-delete). You can therefore either connect the SCSI ID selector-switch for ease of external access/change, or be prepared to select a fixed ID directly on the drive.
If the external HDD will be used with older PowerBooks that do not provide termination power to the external daisy-chain, it will be handy to have an external HDD that can provide its own termination power, and even termination power to the bus. Quantum drives do not universally, or even often, provide this facility. Most of their narrow-SCSI (50-pin) lines have no ID selection and no power selection (the oldest), or ID selection but no power selection (the middling). Their 68-pin drives (more recent) offer a little more in the way of configuration.
If the enclosure that you cited has two external CN-50F ports, one must be occupied by a passive CN-50M terminator, as Unknown_K mentioned, unless the HDD itself offers active or passive termination on its logic board. If you use the on-board termination, the enclosure will have to be the last device in an external daisy-chain. If you don't use the on-board termination, the second CN-50F port can either have another SCSI device daisy-chained from it, or use a plug-in terminator.
The fan question has been answered by LCGuy. It is there for a purpose—no matter why it is presently disconnected—and becomes more important as the capacity, rotational speed and duration of use of the contained HDD are increased.
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