I think the filler is useful to give the laptop increased mechanical stiffness and better balance. And the primary hazard is with charged cells. However uncharged batteries still might have some charge in sections (and hold it for a year or so), and in any case there is a lot of lithium chemical in various forms inside which will not appreciate any moisture from the air leaking in there long term. The risk is not zero. The risk of a filler is smallest if handled gently, avoiding mechanical shocks AND if the laptop NEVER tries to charge it while it is left plugged in. Some batteries have shorted/leaked from being dropped, and the higher capacity versions in a given cell case size are more vulnerable to damage from mechanical shock. An even better filler would be one with no cells and no battery manager board, just the case with stiffening weight inside. You'll have to decide for yourself; I admit to being paranoid about Lithium Ion, and store mine in my fireplace when I'm not in portable mode. Here is why:
A lot of folks are working on safer battery chemistries for portable power and vehicle propulsion. Many of them use the original Sony Lithium Ion battery technology performance, in the 18650 size used in our laptops, as a reference to show just how improved their new thing is in comparison. The next new thing may not be perfect, so how great to have something really bad to compare against...
Several comprehensive studies by Sandia Labs shows that the Lithium Ion charged cell has a thermal runaway problem that can be triggered by temperature alone. Additionally, old cells that have increased cell resistance and uneven current distribution will develop hot spots during use that will further decrease the critical environmental temperature needed to initiate runaway under in use conditions. Soldering can easily exceed the trigger temperature even with zero current flow and a short during soldering, well that could be really exciting.
If you have a high speed connection and want to work on your PhD in batteries, see the highly technical details at:
http://www.osti.gov/bridge/product.biblio.jsp?query_id=0&page=0&osti_id=918751
(3.7 MB pdf download)
http://www.osti.gov/bridge/servlets/purl/921604-QQEfTo/ (2.5 MB PDF download)
Should thermal runaway occur you will not be able to stop it with anything commonly available in households. Not only will the first runaway cell burn to complete destruction, it will most likely heat adjacent cells enough to serially cook off the remainder, slowly at first, then a big fireball.
See the video at
http://www.valence.com/technology/safety_video.html
for what this looks like. Now they started this runaway in a non-conventional manner, but however runaway is started, I think this pretty much shows how it propagates. It could easily set a house on fire.