Physically, yes, it will fit. But in order to actually mount it in the case you are going to need to modify the hell out of the case. You'll need to find some way to physically mount the board (its held in the LC case entirely by clips, there's no actual screw holes in the board), and then you'll need to hack the rear panel a bit so that there is room for all the ports, since the LC backplane is absolutely nothing like an ATX backplane.