I think it can technically be made to work, but there a a couple of reasons you might want to go with eg. an HPV card instead:
- you will need the PM6100 PDS to NuBus adapter, which can be expensive
- you will need to reposition the hard drive and possibly remove the internal bracket to get it to fit, since it looks like a full length 12" card which don't normally fit inside the PM6100 case
- the bandwidth to the HPV PDS card is several times faster than to a NuBus card, not sure the hardware acceleration on the card will make up for it
So unless there are very specific reasons for using the Radius card, it might be better to get an HPV card instead (or even an A/V card) and save the Radius card for a more traditionally NuBus-focused mac.