People would rather have a IIfx now, even if they are more common. But if people keep collecting then sooner or later a Mac II will be worth something.
On the Pro Audio Spectrum 16 ISA card some of the custom chips are just relabeled parts from other manufacturers.
https://www.dosdays.co.uk/topics/retro_review_pas16_pt2.php
My Atari 1040ST and Amiga 500 are stock (except for the common 512K trapdoor RTC) and games run fine on them. I do have 030 accelerators for my A1200 and one of the A2000's.
Unless you are using newly built 030 upgrades, I wouldn't say they are that common.
I don't see any fuses, or 0 Ohm resisters used as cheap fuses.
Pop the ROM out and see if any connectors are mangled (since it has been removed at least once). That ROM socket is from the thru-hole era so every connector in the socket has a pin on the back of the card to check for continuity...